In a large skillet, melt 2 tablespoons of butter over medium heat. Add the minced garlic and sauté for about 1 minute until fragrant, being careful not to burn it.
Add the shrimp to the skillet and season with salt, pepper, and red pepper flakes if using. Cook for 2-3 minutes on each side until the shrimp turn pink and opaque. Remove the shrimp from the skillet and set aside.
In the same skillet, add the remaining 2 tablespoons of butter and the broccoli florets. Sauté for about 5 minutes until the broccoli is bright green and tender-crisp.
While the broccoli is cooking, in a small bowl, whisk together honey, soy sauce, and lemon juice.
Return the shrimp to the skillet with the broccoli and pour the honey garlic mixture over everything. Toss to coat and cook for an additional 2 minutes until heated through.
Serve the shrimp and broccoli over cooked rice or quinoa, drizzling any remaining sauce from the skillet on top.