In a small saucepan, combine honey, hot sauce, unsalted butter, apple cider vinegar, and red pepper flakes. Heat until smooth, about 3-5 minutes.

Rinse the shrimp under cold water and pat dry with paper towels.

In a bowl, whisk together flour, garlic powder, onion powder, smoked paprika, cayenne pepper, salt, and black pepper.

In another bowl, beat together the eggs and milk.

Heat vegetable oil in a frying pan over medium-high heat until 350°F (175°C).

Dredge shrimp in the flour mixture, then dip in the egg wash, and return to the flour for a second coating.

Fry shrimp in batches for 2-3 minutes until golden brown and cooked through.

Toss the fried shrimp with the hot honey sauce in a large bowl.

Serve immediately on a platter with extra sauce for dipping.