In a bowl, combine the garlic powder, onion powder, paprika, salt, and black pepper. Toss the chicken pieces in the spice mixture until well coated.
Set up a breading station: Place the flour in one shallow dish, the beaten eggs in another, and the panko breadcrumbs in a third.
Dredge each piece of chicken in flour, then dip it in the egg, and finally coat it with panko breadcrumbs.
Heat the vegetable oil in a large skillet over medium-high heat. Once hot, add the breaded chicken pieces in a single layer, cooking for about 4-5 minutes on each side or until golden brown and cooked through. Remove and drain on paper towels.
In a small bowl, whisk together the peanut butter, soy sauce, honey, rice vinegar, sesame oil, and water until smooth. Adjust the consistency with more water if needed.
To assemble, place a few pieces of crispy chicken on a cucumber strip, top with a lettuce leaf, and drizzle with creamy peanut sauce. Roll up and enjoy!